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Expeditious synthesis and biological evaluation of novel 2,N6-disubstituted 1,2-dihydro-1,3,5-triazine-4,6-diamines as potential antimalarials

  • Published:2011-06 Issue:6 Volume:46 Page:2022-2030
  • ISSN:0223-5234
  • Container-title:European Journal of Medicinal Chemistry
  • language:en
  • Short-container-title:European Journal of Medicinal Chemistry

Author:

Gravestock David,Rousseau Amanda L.,Lourens Anna C.U.,Moleele Simon S.,van Zyl Robyn L.,Steenkamp Paul A.

Funder

CSIR Biosciences Parliamentary Grant

NRF

University of Johannesburg

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference39 articles.

1. World Malaria Report;WHO,2009

2. Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery;Plowe,2001

3. Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery;Meshnick,2001

4. Role of Specific Cytochrome P450 Isoforms in the Conversion of Phenoxypropoxybiguanide Analogs in Human Liver Microsomes to Potent Antimalarial Dihydrotriazines

5. Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery;Vaidya,2001
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