Discovery of novel SCD1 inhibitors: 5-Alkyl-4,5-dihydro-3H-spiro[1,5-benzoxazepine-2,4′-piperidine] analogs-Reference-Cited by-同舟云学术

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Discovery of novel SCD1 inhibitors: 5-Alkyl-4,5-dihydro-3H-spiro[1,5-benzoxazepine-2,4′-piperidine] analogs

Published:2011-05 Issue:5 Volume:46 Page:1892-1896
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Uto Yoshikazu,Ueno Yuko,Kiyotsuka Yohei,Miyazawa Yuriko,Kurata Hitoshi,Ogata Tsuneaki,Takagi Toshiyuki,Wakimoto Satoko,Ohsumi Jun

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference22 articles.

1. Mechanism of rat liver microsomal stearyl-CoA desaturase. Studies of the substrate specificity, enzyme-substrate interactions, and the function of lipid.

2. The regulation of stearoyl-CoA desaturase (SCD)

3. Recent insights into stearoyl-CoA desaturase-1

4. Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism

5. Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice

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1. Development of Spiro[chromane-2,4′-piperidine]-4(3H)-one Compounds in the Field of Medicinal Chemistry Research (A Review);Russian Journal of General Chemistry;2023-05

2. A Synthetic Overview of Benzoxazines and Benzoxazepines as Anticancer Agents;ChemMedChem;2023-01-16

3. Privileged scaffolds in anti-diabetic drug discovery;Privileged Scaffolds in Drug Discovery;2023

4. Elevated stearoyl-CoA desaturase 1 activity is associated with alcohol-associated liver disease;Alcohol;2022-08

5. 1,5‐Benzoxazepines as a unique and potent scaffold for activity drugs: A review;Archiv der Pharmazie;2021-08-08

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