Distinct novel quinazolinone exhibits selective inhibition in MGC-803 cancer cells by dictating mutant p53 function-Reference-Cited by-同舟云学术

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Distinct novel quinazolinone exhibits selective inhibition in MGC-803 cancer cells by dictating mutant p53 function

Published:2015-05 Issue: Volume:95 Page:377-387
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Zhang Guo-Hai,Xue Wen-Bin,An Yun-Feng,Yuan Jing-Mei,Qin Jiang-Ke,Pan Cheng-Xue,Su Gui-Fa^ORCID

Funder

National Natural Science Foundation of China

Ministry of Education

Guangxi Scientific Research and Technology Development Project

Natural Science Foundation of Guangxi

Ministry of Science and Technology

Science and Technology Development Fund

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference44 articles.

1. Inhibition enhancer of zeste homologue 2 promotes senescence and apoptosis induced by doxorubicin inp53mutant gastric cancer cells

2. Mutant p53 in Cancer: New Functions and Therapeutic Opportunities

3. SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis

4. Understanding the prowess of mutant p53

5. p53 and its mutants in tumor cell migration and invasion

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