The influence and manipulation of acid/base properties in drug discovery
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Molecular Medicine
Reference26 articles.
1. Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist;Chien;Science,2010
2. Structural mechanism for statin inhibition of HMG-CoA reductase;Istvan;Science,2001
3. Acidic and basic drugs in medicinal chemistry: a perspective;Charifson;J Med Chem,2014
4. The significance of acid/base properties in drug discovery;Manallack;Chem Soc Rev,2013
5. A chemogenomic analysis of ionization constants - implications for drug discovery;Manallack;ChemMedChem,2013
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Tuning Ferulic Acid Solubility in Choline-Chloride- and Betaine-Based Deep Eutectic Solvents: Experimental Determination and Machine Learning Modeling;Molecules;2024-08-13
2. Experimental and Machine-Learning-Assisted Design of Pharmaceutically Acceptable Deep Eutectic Solvents for the Solubility Improvement of Non-Selective COX Inhibitors Ibuprofen and Ketoprofen;Molecules;2024-05-14
3. A review on the treatment of intimal hyperplasia with perivascular medical devices: role of mechanical factors and drug release kinetics;Expert Review of Medical Devices;2023-08-10
4. Synthesis, biological evaluation of novel iridium(III) complexes targeting mitochondria toward melanoma B16 cells;European Journal of Medicinal Chemistry;2023-02
5. Trends in small molecule drug properties: A developability molecule assessment perspective;Drug Discovery Today;2022-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3