Kinetics and mechanism of inhibition of serine esterases by fluorinated aminophosphonates

Author:

Makhaeva G.F.,Aksinenko A.Y.,Sokolov V.B.,Baskin I.I.,Palyulin V.A.,Zefirov N.S.,Hein N.D.,Kampf J.W.,Wijeyesakere S.J.,Richardson R.J.

Funder

CRDF

ISTC

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference40 articles.

1. Organophosphorus Pesticides: Organic and Biological Chemistry;Eto,1974

2. Anticholinesterase insecticides;Thompson,2004

3. Interaction of dialkyl(α-carbomethoxy-β,β,β-trifluoroethyl) phosphates with mammalian esterases;Makhaeva;Bioorg. Khim.,1987

4. Esterase profile and analysis of structure-inhibitor selectivity relationships for homologous phosphorylated 1-hydroperfluoroisopropanols;Makhaeva;Dokl. Biochem. Biophys.,2008

5. Synthesis of organophosphates with fluorine-containing leaving groups as serine esterase inhibitors with potential for Alzheimer disease therapeutics;Makhaeva;Bioorg. Med. Chem. Lett.,2009

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