Apigenin attenuates pulmonary hypertension by inducing mitochondria-dependent apoptosis of PASMCs via inhibiting the hypoxia inducible factor 1α–KV1.5 channel pathway-Reference-Cited by-同舟云学术

Apigenin attenuates pulmonary hypertension by inducing mitochondria-dependent apoptosis of PASMCs via inhibiting the hypoxia inducible factor 1α–KV1.5 channel pathway

Published:2020-02 Issue: Volume:317 Page:108942
ISSN:0009-2797
Container-title:Chemico-Biological Interactions
language:en
Short-container-title:Chemico-Biological Interactions

Author:

He Yuanzhou,Fang Xiaoyu,Shi Jing,Li Xiaochen,Xie Min,Liu Xiansheng

Funder

National Key Research and Development Programs of China

National Natural Science Foundation of China

National Key Technology R&D Program of the 12th National Five-year Development Plan

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference34 articles.

1. New and emerging therapies for pulmonary arterial hypertension;Spiekerkoetter;Annu. Rev. Med.,2019

2. Selexipag for the treatment of pulmonary arterial hypertension;Sitbon;N. Engl. J. Med.,2015

3. Impairment of endothelium-dependent pulmonary-artery relaxation in chronic obstructive lung disease;Dinh-Xuan;N. Engl. J. Med.,1991

4. Cell death in the lung: the apoptosis-necroptosis Axis;Sauler;Annu. Rev. Physiol.,2019

5. Mitochondria dysfunction: a novel therapeutic target in pathological lung remodeling or bystander?;Rowlands;Pharmacol. Ther.,2016

Cited by 40 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Unveiling the therapeutic potential of corn silk against hypertension: A critical review;Food Bioscience;2024-12

2. Dietary apigenin ameliorates obesity-related hypertension through TRPV4-dependent vasorelaxation and TRPV4-independent adiponectin secretion;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2024-12

3. Luteolin ameliorates hypoxic pulmonary vascular remodeling in rat via upregulating KV1.5 of pulmonary artery smooth muscle cells;Phytomedicine;2024-09

4. COVID-19-Associated Sepsis: Potential Role of Phytochemicals as Functional Foods and Nutraceuticals;International Journal of Molecular Sciences;2024-08-03

5. Therapeutic potential of natural flavonoids in pulmonary arterial hypertension: A review;Phytomedicine;2024-06