Theacrine ameliorates experimental liver fibrosis in rats by lowering cholesterol storage via activation of the Sirtuin 3-farnesoid X receptor signaling pathway

Author:

Lv Xi-Ting,Wang Ruo-Hong,Liu Xiao-Ting,Ye Yu-Jing,Liu Xin-Yu,Qiao Jing-Da,Wang Guo-EnORCID

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference37 articles.

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2. Anti-fibrotic role and mechanism of Periplaneta americana extracts in CCl4-induced hepatic fibrosis in rats;Li;Acta Biochim. Biophys. Sin.,2018

3. Hepatic stellate cells and fibrosis progression in patients with nonalcoholic fatty liver disease;Feldstein;Clin. Gastroenterol. Hepatol. : the official clinical practice journal of the American Gastroenterological Association,2005

4. Matrix metalloproteinase-1 decorated polymersomes, a surface-active extracellular matrix therapeutic, potentiates collagen degradation and attenuates early liver fibrosis;Geervliet;J. Contr. Release : official journal of the Controlled Release Society,2021

5. Smooth muscle alpha-actin deficiency leads to decreased liver fibrosis via impaired cytoskeletal signaling in hepatic stellate cells;Rockey;Am. J. Pathol.,2019

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