Synthesis and evaluation of novel analogues of vitamin B6 as reactivators of tabun and paraoxon inhibited acetylcholinesterase

Author:

Gašo-Sokač Dajana,Katalinić Maja,Kovarik Zrinka,Bušić Valentina,Kovač Spomenka

Funder

Ministry of Science, Education and Sports of the Republic of Croatia

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference16 articles.

1. Chemical Warfare Agents: Toxicity at Low levels;Somani,2001

2. Organophosphates/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment;Bajgar;Adv. Clin. Chem.,2004

3. Design and structure–activity relationships of antidotes to organophosphorus anticholinesterase agents;Gray;Drug Metab. Rev.,1984

4. Review of oximes available for the treatment of nerve agent poisoning;Dawson;J. Appl. Toxicol.,1994

5. Pyridinium, imidazolium, and quinucludinium oximes: synthesis, interaction with native and phosphylated cholinesterases, and antidotes against organophosphorus compounds;Primožič;J. Med. Chem. Def.,2004

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