The in vitro protective effects of the three novel nanomolar reversible inhibitors of human cholinesterases against irreversible inhibition by organophosphorous chemical warfare agents

Author:

Vitorović-Todorović Maja D.,Worek Franz,Perdih Andrej,Bauk Sonja Đ.,Vujatović Tamara B.,Cvijetić Ilija N.

Funder

Serbian Ministry of Education Science and Technological Development

Serbian Ministry of Defence, and by the German Ministry of Defence

Ministry of Higher Education, Science and Technology of the Republic of Slovenia

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference47 articles.

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3. Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes;Worek;Biochem. Pharmacol.,2004

4. Inhibition of cholinesterases with cationic phosphonyl oximes highlights distinctive properties of the charged pyridine groups of quaternary oxime reactivators;Ashani;Biochem. Pharmacol.,2003

5. Formation and disposition of diethylphosphoryl-obidoxime, a potent anticholinesterase that is hydrolyzed by human paraoxonase (PON1);Kiderlen;Biochem. Pharmacol.,2005

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