Investigation of the effects of axitinib on the pharmacokinetics of loperamide and its main metabolite N-demethylated loperamide in rats by UPLC-MS/MS-Reference-Cited by-同舟云学术

Investigation of the effects of axitinib on the pharmacokinetics of loperamide and its main metabolite N-demethylated loperamide in rats by UPLC-MS/MS

Published:2019-09 Issue: Volume:310 Page:108744
ISSN:0009-2797
Container-title:Chemico-Biological Interactions
language:en
Short-container-title:Chemico-Biological Interactions

Author:

Lin Qian-meng,Pang Ni-hong,Li Ying-hui,Huang Huan-le,Zhang Xiao-dan,Hu Guo-xin,Wang Zeng-shou

Funder

School of Pharmaceutical Sciences

Wenzhou Medical University

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference38 articles.

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3. Interaction of ritonavir-boosted tipranavir with loperamide does not result in loperamide-associated neurologic side effects in healthy volunteers;Mukwaya;Antimicrob. Agents Chemother.,2005

4. Abuse potential of loperamide;Jaffe;Clin. Pharmacol. Ther.,1980

5. Loperamide misuse and abuse;Miller;J. Am. Pharm. Assoc. : J. Am. Pharm. Assoc. JAPhA,2017

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