The cap’n’collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics

Author:

Higgins Larry G.,Hayes John D.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference77 articles.

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2. Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2;Aleksunes;Toxicol. Appl. Pharmacol.,2008

3. DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust;Aoki;Toxicol. Appl. Pharmacol.,2001

4. The GI-GPx gene is a target for Nrf2;Banning;Mol. Cell. Biol.,2005

5. Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines;Bonnesen;Cancer Res.,2001

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