Isoquercetin upregulates antioxidant genes, suppresses inflammatory cytokines and regulates AMPK pathway in streptozotocin-induced diabetic rats

Author:

Jayachandran Muthukumaran,Wu Ziyuan,Ganesan Kumar,Khalid Sumbul,Chung S.M.,Xu Baojun

Funder

Beijing Normal University-Hong Kong Baptist University United International College

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference31 articles.

1. Hyperglycemia-induced oxidative stress and its role in diabetes mellitus related cardiovascular diseases;Fiorentino;Curr. Pharmaceut. Des.,2013

2. The Nrf2/Keap1/ARE pathway and oxidative stress as a therapeutic target in type II diabetes mellitus;David;J. Diab. Res.,2017

3. Development of an antioxidant biomaterial by promoting the deglycosylation of rutin to isoquercetin and quercetin;Cruz-Zuniga;Food Chem.,2016

4. Inhibitory effect of quercetin on carrageenan-induced inflammation in rats;Morikawa;Life Sci.,2003

5. Flavonoid glycosides from the leaves of Eucommia ulmoides O with glycation inhibitory activity;Kim;J. Ethnopharmacol.,2004

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