Enantioselective inhibition of Cytochrome P450-mediated drug metabolism by a novel antithrombotic agent, S002-333: Major effect on CYP2B6

Author:

Bhateria Manisha,Ramakrishna Rachumallu,Puttrevu Santosh Kumar,Saxena Anil K.,Bhatta Rabi Sankar

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference50 articles.

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2. New antithrombotic drugs: American college of chest physicians evidence-based clinical practice guidelines *;Weitz;CHEST J.,2008

3. S. Gaur, Z. Fatima, A. Dixit, Z. Ali, W. Surin, K. Kapoor, K. Bhutani, M. Ansari, M. Dikshit, A. Saxena, 2-Alkyl/aryl sulphonyl-1, 2, 3, 4-tetrahydro-9h-pyrido (3, 4-b) indole-3-carboxylic acid esters/amides useful as antithrombotic agents, U.S. Patent Application 11/842,674, 2007.

4. Bioanalytical method development and validation for simultaneous estimation of (R)-and (S)-isomers of S002-333: a potent novel anti-thrombotic agent using LC–MS/MS;Bhatta;Med. Chem. Res.,2011

5. The Impact of Stereochemistry on Drug Development and Use;Aboul-Enein,1997

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