Synthesis of 11C-labeled desipramine and its metabolite 2-hydroxydesipramine: Potential radiotracers for pet studies of the norepinephrine transporter

Author:

Van Dort Marcian E.,Kim Jae-Hoon,Tluczek Louis,Wieland Donald M.

Publisher

Elsevier BV

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Molecular Medicine

Reference14 articles.

1. A facile synthetic route to hydroxy metabolites of tricyclic antideptessants;Adamczyk,1991

2. Evidence for reduction of norepinephrine uptake sites in the failing human heart;Bohm;J. Am. Coll. Cardiol.,1995

3. The noradrenaline transporter of the neuronal plasma membrane;Bonisch;Ann. N. Y. Acad. Sci.,1994

4. Recommendations for a practical production of [11C]methyl iodide;Crouzel;Appl. Radiat. Isot.,1987

5. The production in high yield of N′-(4-[11C]methyl)-imipramine;Denutte;J. Nucl. Med.,1983

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