Thymidylate synthase activity in leukocytes from patients with chronic myelocytic leukemia and acute lymphocytic leukemia and its inhibition by phenanthroindolizidine alkaloids pergularinine and tylophorinidine

Author:

Narasimha Rao K,Bhattacharya R.K,Venkatachalam S.R

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference40 articles.

1. Studies on normal and leukemic leukocytes. IV. Tetrahydrofolate-dependent enzyme systems and dihydrofolic reductase;Bertino;J. Clin. Invest.,1963

2. I.R.C. Bick, W. Sinchai, Phenanthroindolizidine and phenanthroquinolizidine alkaloids, in: R.G.A. Rodrigo (Ed.), The Alkaloids: Chemistry and Physiology, Vol. XIX, Academic Press, New York, 1981, pp. 193–220.

3. R.L. Blakley, Pteridines in the metabolism of purines, pyrimidines and their derivatives, in: A. Neuberger, E.L. Tatum (Eds.), The Biochemistry of Folic Acid and Related Pteridines, North-Holland, Amsterdam, 1969, pp. 219–266.

4. A simple efficient liquid scintillation for counting aqueous solutions in a liquid scintillation counter;Bray;Anal. Biochem.,1960

5. The catalytic mechanism and structure of thymidylate synthase;Carreras;Annu. Rev. Biochem.,1995

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