Selective induction of apoptosis in mouse and human lung epithelial cell lines by the tert-butyl hydroxylated metabolite of butylated hydroxytoluene: a proposed role in tumor promotion

Author:

Dwyer-Nield Lori D.,Thompson John A.,Peljak Gertraud,Squier Margaret K.T.,Barker Tobias D.,Parkinson Andrew,Cohen J.John,Dinsdale David,Malkinson Alvin M.

Publisher

Elsevier BV

Subject

Toxicology

Reference48 articles.

1. Lung injury induced by butylated hydroxytoluene: cytodynamic and biochemical studies in mice;Adamson;Lab. Invest.,1977

2. Apoptosis is a major pathway responsible for the resolution of type II pneumocytes in acute lung injury;Bardales;Am. J. Pathol.,1996

3. The price of independence;Baserga;Exp. Cell Res.,1997

4. Oxidation of butylated hydroxytoluene to toxic metabolites: Factors influencing hydroxylation and quinone methide formation by hepatic and pulmonary microsomes;Bolton;Drug Metab. Dispos.,1991

5. Metabolic activation of butylated hydroxytoluene by mouse bronchiolar Clara cells;Bolton;Toxicol. Appl. Pharmacol.,1993

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