Grb2/Ash binds directly to tyrosines 1068 and 1086 and indirectly to tyrosine 1148 of activated human epidermal growth factor receptors in intact cells.-Reference-Cited by-同舟云学术

Grb2/Ash binds directly to tyrosines 1068 and 1086 and indirectly to tyrosine 1148 of activated human epidermal growth factor receptors in intact cells.

Published:1994-12 Issue:49 Volume:269 Page:31310-31314
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Okutani T,Okabayashi Y,Kido Y,Sugimoto Y,Sakaguchi K,Matuoka K,Takenawa T,Kasuga M

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference54 articles.

1. Function of Ras as a molecular switch in signal transduction.

2. Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity.

3. Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

4. Platelet-derived growth factor stimulates formation of active p21ras.GTP complex in Swiss mouse 3T3 cells.

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