Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitro-camptothecin.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference55 articles.
1. DNA TOPOISOMERASES
2. Supercoiling of the DNA template during transcription.
3. Evidence for an intermediate with a single-strand break in the reaction catalyzed by the DNA untwisting enzyme.
4. Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I.
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