Comparison of kinetic properties between two mammalian ras p21 GDP/GTP exchange proteins, ras guanine nucleotide-releasing factor and smg GDP dissociation stimulation.-Reference-Cited by-同舟云学术

Comparison of kinetic properties between two mammalian ras p21 GDP/GTP exchange proteins, ras guanine nucleotide-releasing factor and smg GDP dissociation stimulation.

Published:1993-12 Issue:34 Volume:268 Page:25542-25546
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Orita S,Kaibuchi K,Kuroda S,Shimizu K,Nakanishi H,Takai Y

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference34 articles.

1. ras GENES

2. All ras proteins are polyisoprenylated but only some are palmitoylated

3. p21ras is modified by a farnesyl isoprenoid.

4. A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

5. Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation.

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