The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis. Evidence for function as the binding site for a translational repressor.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference15 articles.
1. Novel mechanism for translational control in regulation of ferritin synthesis by iron.
2. Both subunits of rat liver ferritin are regulated at a translational level by iron induction
3. Influence of altered transcription on the translational control of human ferritin expression.
4. A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron.
5. Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region.
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