The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca2+.-Reference-Cited by-同舟云学术

The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca2+.

Published:1985-10 Issue:24 Volume:260 Page:13035-13040
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Moore M,Thor H,Moore G,Nelson S,Moldéus P,Orrenius S

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference47 articles.

1. Species differences in hepatic glutathione depletion, covalent binding and hepatic necrosis after acetaminophen

2. Acetaminophen-Induced Hepatic Necrosis and Renal Failure

3. PLASMA-PARACETAMOL HALF-LIFE AND HEPATIC NECROSIS IN PATIENTS WITH PARACETAMOL OVERDOSAGE

4. Paracetamol metabolism and toxicity in isolated hepatocytes from rat and mouse

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