Expression of rat liver phenylalanine hydroxylase in insect cells and site-directed mutagenesis of putative non-heme iron-binding sites.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference51 articles.
1. The activation of rat liver phenylalanine hydroxylase by limited proteolysis, lysolecithin, and tocopherol phosphate. Changes in conformation and catalytic properties.
2. Characterization of phenylalanine hydroxylase
3. THE MEASUREMENT OF ZERO FIELD SPLITTING AND THE DETERMINATION OF LIGAND COMPOSITION IN MONONUCLEAR NONHEME IRON PROTEINS
4. Catecholate LMCT bands as probes for the active sites of nonheme iron oxygenases
5. Isolation and sequence of a cDNA clone which contains the complete coding region of rat phenylalanine hydroxylase. Structural homology with tyrosine hydroxylase, glucocorticoid regulation, and use of alternate polyadenylation sites.
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1. Characterization of metal ligand mutants of phenylalanine hydroxylase: Insights into the plasticity of a 2-histidine-1-carboxylate triad;Archives of Biochemistry and Biophysics;2008-07
2. Predicted Effects of Missense Mutations on Native-State Stability Account for Phenotypic Outcome in Phenylketonuria, a Paradigm of Misfolding Diseases;The American Journal of Human Genetics;2007-11
3. Structural Studies on Phenylalanine Hydroxylase and Implications Toward Understanding and Treating Phenylketonuria;Pediatrics;2003-12-01
4. Site-Directed Mutagenesis Studies on a Putative Fifth Iron Ligand of Mouse 8S-Lipoxygenase: Retention of Catalytic Activity on Mutation of Serine-558 to Asparagine, Histidine, or Alanine;Archives of Biochemistry and Biophysics;2001-02
5. Functional Analysis, Using in Vitro Mutagenesis, of Amino Acids Located in the Phenylalanine Hydroxylase Active Site;Archives of Biochemistry and Biophysics;2000-12
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