Evidence for specific base catalysis in N-dealkylation reactions catalyzed by cytochrome P450 and chloroperoxidase. Differences in rates of deprotonation of aminium radicals as an explanation for high kinetic hydrogen isotope effects observed with peroxidases.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference51 articles.
1. Dynamics of proton transfer from cation radicals. Kinetic and thermodynamic acidities of cation radicals of NADH analogs
2. Electron acceptor function of O2 in radical N-demethylation reactions catalyzed by hemeproteins
3. The catalytic mechanism of cytochrome P-450. Spin-trapping evidence for one-electron substrate oxidation.
4. A new metabolite of methamphetamine; evidence for formation ofN-[(1-methyl-2-phenyl)ethyl]ethanimineN-oxide
5. Identification of the fifth axial heme ligand of chloroperoxidase.
Cited by 78 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Structure of the green heme isolated from allylbenzene-modified chloroperoxidase: A novel heme architecture implicating the mechanisms of CPO inactivation and epoxidation;Computational and Structural Biotechnology Journal;2023
2. Nanosized CdS as a Reusable Photocatalyst: The Study of Different Reaction Pathways between Tertiary Amines and Aryl Sulfonyl Chlorides through Visible-Light-Induced N-Dealkylation and C–H Activation Processes;The Journal of Organic Chemistry;2021-01-19
3. Visible light-induced oxidative N-dealkylation of alkylamines by a luminescent osmium(vi) nitrido complex;Chemical Science;2021
4. Mechanistic studies on the drug metabolism and toxicity originating from cytochromes P450;Drug Metabolism Reviews;2020-07-02
5. Study on forced degradation behaviour of dofetilide by LC-PDA and Q-TOF/MS/MS: Mechanistic explanations of hydrolytic, oxidative and photocatalytic rearrangement of degradation products;Journal of Pharmaceutical and Biomedical Analysis;2020-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3