Side chain hydroxylations in biosynthesis of cholic acid. 25- and 26-Hydroxylation of 5beta-cholestane-3alpha, 7alpha, 12alpha-triol by reconstituted systems from rat liver microsomes.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference20 articles.
1. Hydroxylations in biosynthesis and metabolism of bile acids
2. Oxidation of 5beta-Cholestane-3alpha, 7alpha, 12alpha-triol by Rat Liver Microsomes
3. A Biochemical Abnormality in Cerebrotendinous Xanthomatosis IMPAIRMENT OF BILE ACID BIOSYNTHESIS ASSOCIATED WITH INCOMPLETE DEGRADATION OF THE CHOLESTEROL SIDE CHAIN
4. Bile alcohol metabolism in man. Conversion of 5beta-cholestane-3alpha, 7alpha,12alpha, 25-tetrol to cholic acid.
5. 7α-Hydroxylation of taurodeoxycholic acid by a reconstituted system from rat liver microsomes
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1. Biosynthesis of bile acids in mammalian liver;European Journal of Drug Metabolism and Pharmacokinetics;2006-09
2. Side Chain Hydroxylations in Bile Acid Biosynthesis Catalyzed by CYP3A Are Markedly Up-regulated in Cyp27 Mice but Not in Cerebrotendinous Xanthomatosis;Journal of Biological Chemistry;2001-09
3. Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27−/− mice and CTX;Journal of Lipid Research;2001-02
4. Regulation of 25- and 27-hydroxylation side chain cleavage pathways for cholic acid biosynthesis in humans, rabbits, and mice: assay of enzyme activities by high-resolution gas chromatography–mass spectrometry;Journal of Lipid Research;2000-03
5. Sterol 26-Hydroxylase;Cytochrome P450;1993
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