Structural analysis and amphiphilic properties of a chemically synthesized mitochondrial signal peptide.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference18 articles.
1. The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix.
2. A leader peptide is sufficient to direct mitochondrial import of a chimeric protein.
3. Import and processing of hybrid proteins by mammalian mitochondria in vitro.
4. The first twelve amino acids of a yeast mitochondrial outer membrane protein can direct a nuclear-coded cytochrome oxidase subunit to the mitochondrial inner membrane.
5. A synthetic signal peptide blocks import of precursor proteins destined for the mitochondrial inner membrane or matrix.
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