Site-directed mutagenesis in human tissue-plasminogen activator. Distinguishing sites in the amino-terminal region required for full fibrinolytic activity and rapid clearance from the circulation.-Reference-Cited by-同舟云学术

Site-directed mutagenesis in human tissue-plasminogen activator. Distinguishing sites in the amino-terminal region required for full fibrinolytic activity and rapid clearance from the circulation.

Published:1990-04 Issue:10 Volume:265 Page:5540-5545
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Ahern T J,Morris G E,Barone K M,Horgan P G,Timony G A,Angus L B,Henson K S,Stoudemire J B,Langer-Safer P R,Larsen G R

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference29 articles.

1. Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

2. Pharmacokinetics and Effects on Fibrinolytic and Coagulation Parameters of Two Doses of Recombinant Tissue-Type Plasminogen Activator in Healthy Volunteers

3. Pharmacokinetic and distribution analysis of variant forms of tissue- type plasminogen activator with prolonged clearance in rat

4. Human fibronectin metabolism.

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