Pseudomonas exotoxin A mutants. Replacement of surface exposed residues in domain II with cysteine residues that can be modified with polyethylene glycol in a site-specific manner.-Reference-Cited by-同舟云学术

Pseudomonas exotoxin A mutants. Replacement of surface exposed residues in domain II with cysteine residues that can be modified with polyethylene glycol in a site-specific manner.

Published:1994-03 Issue:10 Volume:269 Page:7610-7616
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Kuan C.T.,Wang Q.C.,Pastan I.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference36 articles.

1. Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution.

2. Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin.

3. Alteration of a protease-sensitive region of Pseudomonas exotoxin prolongs its survival in the circulation of mice.

4. Routes to active proteins from transformed microorganisms

5. Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagent

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