Drug-mediated induction of cytochrome(s) P-450 and drug metabolism in cultured hepatocytes maintained in chemically defined medium.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference39 articles.
1. Drug Metabolism in Adult Rat Hepatocytes in Primary Monolayer Culture
2. PARENCHYMAL CELLS FROM ADULT RAT LIVER IN NONPROLIFERATING MONOLAYER CULTURE
3. Effects by heme, insulin, and serum albumin on heme and protein synthesis in chick embryo liver cells cultured in a chemically defined medium, and a spectrofluorometric assay for porphyrin composition.
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1. Induction of Drug-Metabolizing Enzymes by Phenobarbitone: Structural and Biochemical Aspects;Novartis Foundation Symposia;2008-05-30
2. TOXICOLOGICAL METHODS TO STUDY MECHANISMS OF NATURALLY OCCURRING ANTICARCINOGENS;Food and Cancer Prevention;2005
3. Induction of Drug Metabolism: The Role of Nuclear Receptors;Pharmacological Reviews;2003-12
4. Induction of cytochrome P450 2B1 by pyrethroids in primary rat hepatocyte cultures11Abbreviations: CYP, cytochrome P450; EGF, epidermal growth factor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; MC, methylcholanthrene; PB, phenobarbital; PBO, piperonyl butoxide; PBREM, phenobarbital-responsive enhancer module; and PROD, pentoxyresorufin-O-depentylase.;Biochemical Pharmacology;2001-07
5. Cytochrome P450 enzyme activity and protein expression in primary porcine enterocyte and hepatocyte cultures;Xenobiotica;2000-01
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