“Thrombin” receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides.-Reference-Cited by-同舟云学术

“Thrombin” receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides.

Published:1991-10 Issue:28 Volume:266 Page:18435-18438
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Huang R.S.,Sorisky A.,Church W.R.,Simons E.R.,Rittenhouse S.E.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference23 articles.

1. Production of diglyceride from phosphatidylinositol in activated human platelets.

2. Inositol 1,4,5-trisphosphate and inositol 1,2-cyclic 4,5-trisphosphate are minor components of total mass of inositol trisphosphate in thrombin-stimulated platelets. Rapid formation of inositol 1,3,4-trisphosphate.

3. Protein kinase C regulates the stimulated accumulation of 3-phosphorylated phosphoinositides in platelets

4. Human platelets form 3-phosphorylated phosphoinositides in response to alpha-thrombin, U46619, or GTP gamma S.

5. Thrombin stimulates the production of a novel polyphosphoinositide in human platelets.

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