Tumor-promoting phorbol esters increase the Km of the ATP-binding site of the insulin receptor kinase from rat adipocytes.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference28 articles.
1. Phorbolesters enhance basal D-glucose transport but inhibit insulin stimulation of D-glucose transport and insulin binding in isolated rat adipocytes
2. Insulin Stimulates the Phosphorylation of the 95,000-Dalton Subunit of Its Own Receptor
3. Insulin receptor phosphorylation in intact adipocytes and in a cell-free system
4. Tyrosine-specific protein kinase activity is associated with the purified insulin receptor.
5. Receptor-mediated phosphorylation of the hepatic insulin receptor: Evidence that the Mr 95,000 receptor subunit is its own kinase
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