In vitro and in vivo antitumour activity and cellular pharmacological properties of new platinum–iminoether complexes with different configuration at the iminoether ligands

Author:

Coluccia Mauro,Nassi Anna,Boccarelli Angela,Giordano Domenico,Cardellicchio Nicola,Locker Daniel,Leng Marc,Sivo Maria,Intini Francesco P.,Natile Giovanni

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Biochemistry

Reference19 articles.

1. Ligand effects in platinum binding to DNA. A comparison of DNA binding properties for cis- and trans-[PtCl2(amine)2] (amine = NH3, pyridine)

2. A trans-platinum complex showing higher antitumor activity than the cis congeners

3. Platinum(II) complexes containing iminoethers: a trans platinum antitumour agent

4. G. Natile, M. Coluccia, in: M.J. Clarke, P.J. Sadler (Eds.), Topics in Biological Inorganic Chemistry, vol. 1, Metallopharmaceuticals I: DNA Interactions, Springer, Berlin, 1999, pp. 73–98.

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