Ceramide and glucosylceramide upregulate expression of the multidrug resistance gene MDR1 in cancer cells

Author:

Gouazé-Andersson Valérie,Yu Jing Y.,Kreitenberg Adam J.,Bielawska Alicja,Giuliano Armando E.,Cabot Myles C.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference62 articles.

1. Mechanisms of cancer drug resistance;Gottesman;Annu. Rev. Med.,2002

2. The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein;Ueda;Biochem. Biophys. Res. Commun.,1986

3. The ABC transporter genes of Plasmodium falciparum and drug resistance;Peel;Drug Resist. Updat.,2001

4. ABC transporters in Leishmania and their role in drug resistance;Ouellette;Drug Resist. Updat.,1998

5. Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy;Gouaze;Mol. Cancer Ther.,2004

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