The association between UGT1A1 polymorphisms and treatment toxicities of liposomal irinotecan
Author:
Funder
National Health Research Institutes
Ministry of Science and Technology, Taiwan
Kaohsiung Medical University
Publisher
Elsevier BV
Subject
Cancer Research,Oncology
Reference19 articles.
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2. Phase I study of nanoliposomal irinotecan (PEP02) in advanced solid tumor patients;Chang;Cancer Chemother Pharmacol,2015
3. A phase I dose-escalation study of PEP02 (irinotecan liposome injection) in combination with 5-fluorouracil and leucovorin in advanced solid tumors;Chiang;BMC Cancer,2016
4. Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes;Iyer;J Clin Invest,1998
5. UGT1A1 gene variations and irinotecan treatment in patients with metastatic colorectal cancer;Marcuello;Br J Cancer,2004
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1. Nanoliposomal irinotecan and fluorouracil plus leucovorin versus fluorouracil plus leucovorin in patients with cholangiocarcinoma and gallbladder carcinoma previously treated with gemcitabine-based therapies (AIO NALIRICC): a multicentre, open-label, randomised, phase 2 trial;The Lancet Gastroenterology & Hepatology;2024-08
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3. Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with metastatic colorectal cancer;ESMO Open;2023-06
4. Real-World Data Validation of NAPOLI-1 Nomogram for the Prediction of Overall Survival in Metastatic Pancreatic Cancer;Cancers;2023-02-05
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