Pooled safety analysis from phase III studies of trifluridine/tipiracil in patients with metastatic gastric or gastroesophageal junction cancer and metastatic colorectal cancer

Author:

Van Cutsem E.,Hochster H.,Shitara K.,Mayer R.,Ohtsu A.,Falcone A.,Yoshino T.,Doi T.,Ilson D.H.,Arkenau H.-T.,George B.,Benhadji K.A.,Makris L.,Tabernero J.

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference31 articles.

1. A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA;Emura;Int J Oncol,2004

2. Structure and activity of specific inhibitors of thymidine phosphorylase to potentiate the function of antitumor 2’-deoxyribonucleosides;Fukushima;Biochem Pharmacol,2000

3. A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells;Emura;Int J Mol Med,2004

4. LONSURF® (trifluridine and tipiracil) tablets [prescribing information],2019

5. Randomized trial of TAS-102 for refractory metastatic colorectal cancer;Mayer;N Engl J Med,2015

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