Phase Ib study of talimogene laherparepvec in combination with atezolizumab in patients with triple negative breast cancer and colorectal cancer with liver metastases

Author:

Hecht J.R.ORCID,Raman S.S.,Chan A.ORCID,Kalinsky K.ORCID,Baurain J.-F.ORCID,Jimenez M.M.,Garcia M.M.ORCID,Berger M.D.ORCID,Lauer U.M.,Khattak A.,Carrato A.ORCID,Zhang Y.ORCID,Liu K.,Cha E.ORCID,Keegan A.ORCID,Bhatta S.,Strassburg C.P.,Roohullah A.

Funder

Amgen

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference29 articles.

1. Molecular pathways: mechanism of action for talimogene laherparepvec, a new oncolytic virus immunotherapy;Kohlhapp;Clin Cancer Res,2016

2. ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties;Liu;Gene Ther,2003

3. IMLYGIC® (talimogene laherparepvec). Full Prescribing Information. Thousand Oaks, CA: Amgen Inc; 2023. Available at imlygic_pi.ashx (amgen.com). Accessed February 22, 2023.

4. IMLYGICTM. Summary of Product Characteristics. London, UK: European Medicines Agency; 2020. Available at https://www.ema.europa.eu/en/documents/product-information/imlygic-epar-product-information_en.pdf. Accessed February 22, 2023.

5. TECENTRIQ (Atezolizumab). Full Prescribing Information. South San Francisco, CA: Genentech Inc.; 2022. Available at tecentriq_prescribing.pdf (gene.com). Accessed February 22, 2023.

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