Identification of a new metabolite of macrolide immunosuppressant, like rapamycin and SDZ RAD, using high performance liquid chromatography and electrospray tandem mass spectrometry-Reference-Cited by-同舟云学术

Identification of a new metabolite of macrolide immunosuppressant, like rapamycin and SDZ RAD, using high performance liquid chromatography and electrospray tandem mass spectrometry

Published:2000-06-01 Issue:6 Volume:11 Page:516-525
ISSN:1044-0305
Container-title:Journal of the American Society for Mass Spectrometry
language:en
Short-container-title:J. Am. Soc. Mass Spectrom.

Author:

Hallensleben Katrin¹,Raida Manfred²,Habermehl Gerhard¹

Affiliation:

1. Chemisches Institut/Haus-Nr. 123, c/o Prof. Dr. G. Habermehl, Tieraerztliche Hochschule Hannover, Bischofsholer Damm 15, D-30173, Hannover, Germany

2. Niedersaechsisches Institut für Peptidforschung, Hannover, Germany

Publisher

American Chemical Society (ACS)

Subject

Spectroscopy,Structural Biology

Link

https://pubs.acs.org/doi/pdf/10.1016/S1044-0305%2800%2900123-9

Reference19 articles.

1. Biosynthesis of Erythromycin and Rapamycin

2. SDZ RAD, A NEW RAPAMYCIN DERIVATIVE

3. SDZ RAD, A NEW RAPAMYCIN DERIVATIVE

4. Chan, K.; Wang, P.; Sakuma, J.; Cochran, D.; Humber, L.; Sisenwine, S. Characterisation of biliary rapamycin metabolites by ionspray liquid chromatography/mass spectrometry. Proceedings of the 41st ASMS Conference on Mass Spectrometry. pp 545a–545b.

5. High Performance Liquid Chromatographic Isolation, Spectroscopic Characterization, and Immunosuppressive Activities of Two Rapamycin Degradation Products

Cited by 31 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structural Identification of Zotarolimus (ABT-578) Metabolites Generated by Human Liver Microsomes Using Ion-Trap and High-Resolution Time-of-Flight Mass Spectrometry in Combination with the Analysis of Fragmentation Patterns;Metabolites;2023-10-19

2. Temsirolimus metabolic pathways revisited;Xenobiotica;2019-10-23

3. Drug metabolites and their effects on the development of adverse reactions: Revisiting Lipinski’s Rule of Five;International Journal of Pharmaceutics;2018-10

4. STABILITY INDICATING ASSAY METHOD OF SIROLIMUS USING HPLC AND SEPARATION OF ACID DEGRADANT BY HPTLC;INDIAN DRUGS;2018-04-28

5. Rapamycin-loaded solid lipid nanoparticles: Morphology and impact of the drug loading on the phase transition between lipid polymorphs;Colloids and Surfaces A: Physicochemical and Engineering Aspects;2016-08