Hyperpolarized 13C NMR for longitudinal in-cell metabolism using a mobile 3D cell culture system

Author:

Mathiassen T.B.W.,Høgh A.E.,Karlsson M.,Katsikis S.,Wang K.,Pennestri M.,Ardenkjær-Larsen J.H.,Jensen P.R.ORCID

Funder

Danish National Research Foundation

Novo Nordisk Foundation

Publisher

Elsevier BV

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference27 articles.

1. Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR;Ardenkjaer-Larsen,2003

2. Hyperpolarized 13C MRI: path to clinical translation in oncology;Kurhanewicz;Neoplasia,2019

3. Probing treatment response of glutaminolytic prostate cancer cells to natural drugs with hyperpolarized [5-(13) C]glutamine;Canapè;Magn. Reson. Med.,2015

4. Treatment with the MEK inhibitor U0126 induces decrease hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells;Lodi;NMR Biomed.,2013

5. Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors;Gallagher,2009

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