Expression of glutathione peroxidase 2 is associated with not only early hepatocarcinogenesis but also late stage metastasis

Author:

Suzuki Shugo,Pitchakarn Pornsiri,Ogawa Kumiko,Naiki-Ito Aya,Chewonarin Teera,Punfa Wanisa,Asamoto Makoto,Shirai Tomoyuki,Takahashi Satoru

Funder

Society for Promotion of Toxicological Pathology of Nagoya, Japan

Publisher

Elsevier BV

Subject

Toxicology

Reference23 articles.

1. Downregulation of proapoptotic proteins Bax and Bcl-X(S) in p53 overexpressing hepatocellular carcinomas;Beerheide;Biochem. Biophys. Res. Commun.,2000

2. Glutathione peroxidases in different stages of carcinogenesis;Brigelius-Flohe;Biochim. Biophys. Acta,2009

3. Effects of radical oxygen species and NO: formation of intracellular hypoxia and activation of matrix metalloproteinases in tumor tissues;Burlaka;Exp. Oncol.,2006

4. Molecular expression analysis of beta-naphthoflavone-induced hepatocellular tumors in rats;Dewa;Toxicol. Pathol.,2009

5. Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor;Fernandez-Patron;Circ. Res.,1999

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