Increasing confidence in new approach methodologies for inhalation risk assessment with multiple end point assays using 5-day repeated exposure to 1,3-dichloropropene

Author:

Paudel Iru,Barutcu A. Rasim,Samuel Raymond,Moreau Marjory,Slattery Scott D.,Scaglione Jamie,Recio Leslie

Funder

American Chemistry Council

Publisher

Elsevier BV

Subject

Toxicology

Reference32 articles.

1. Application of transcriptomic data, visualization tools and bioinformatics resources for informing mode of action;Andersen;Curr. Opin. Toxicol.,2018

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3. Targeted omics analyses, and metabolic enzyme activity assays demonstrate maintenance of key mucociliary characteristics in long term cultures of reconstituted human airway epithelia;Baxter;Toxicol. Vitr.,2015

4. Next generation software for functional trend analysis;Berriz;Bioinformatics,2009

5. Dietz FK, H.E., Kastl P. (1985). 1,3-dichloropropene: pharmacokinetics, effect on tissue non-protein sulfhydryls, and macromolecular binding in fisher-344 rats and b6c3f1 mice following oral administration. Dow Chemical Company. Submitted to the U.S. Environmental Protection Agency under TSCA Section 8D. OTS0517371.

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