Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia telangiectasia and Rad3-related-Reference-Cited by-同舟云学术

Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia telangiectasia and Rad3-related

Published:2015-05 Issue: Volume:331 Page:35-46
ISSN:0300-483X
Container-title:Toxicology
language:en
Short-container-title:Toxicology

Author:

Beggs Kevin M.,Maiuri Ashley R.,Fullerton Aaron M.,Poulsen Kyle L.,Breier Anna B.,Ganey Patricia E.,Roth Robert A.

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Toxicology

Reference69 articles.

1. Inhibitory effect of antipsychotic drugs on the con A- and LPS-induced proliferative activity of mouse splenocytes: a possible mechanism of action;Basta-Kaim;J. Physiol. Pharmacol.,2006

2. Molecular mechanisms of hepatocellular apoptosis induced by trovafloxacin-tumor necrosis factor-alpha interaction;Beggs;Toxicol. Sci.,2014

3. The chemistry and biological profile of trovafloxacin;Brighty;J. Antimicrob. Chemother.,1997

4. ERK and cell death: mechanisms of ERK-induced cell death – apoptosis, autophagy and senescence;Cagnol;FEBS J.,2010

5. Multiple roles of the cell cycle inhibitor p21(CDKN1A) in the DNA damage response;Cazzalini;Mutat. Res.,2010

Cited by 20 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mapping Interindividual Variability of Toxicodynamics Using High-Throughput Transcriptomics and Primary Human Hepatocytes from Fifty Donors;Environmental Health Perspectives;2024-03

2. Mechanistic Understanding of Idiosyncratic Drug-Induced Hepatotoxicity Using Co-Cultures of Hepatocytes and Macrophages;Antioxidants;2023-06-21

3. Cell Dome as an Evaluation Platform for Organized HepG2 Cells;Cells;2022-12-23

4. Trovafloxacin drives inflammation-associated drug-induced adverse hepatic reaction by changing macrophage polarization;Toxicology in Vitro;2022-08

5. Study on the Mechanism of Mesaconitine-Induced Hepatotoxicity in Rats Based on Metabonomics and Toxicology Network;Toxins;2022-07-14