Transcriptional and posttranslational mechanisms modulating the expression of the cytochrome P450 1A1 gene by lead in HepG2 cells: A role of heme oxygenase

Author:

Korashy Hesham M.,El-Kadi Ayman O.S.

Funder

Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery

Publisher

Elsevier BV

Subject

Toxicology

Reference43 articles.

1. Mercury modulates the CYP1A1 at transcriptional and posttranslational levels in human hepatoma HepG2 cells;Amara;Toxicol. Lett.,2010

2. Down-regulation of the detoxifying enzyme NAD(P)H:quinone oxidoreductase 1 by vanadium in Hepa 1c1c7 cells;Anwar-Mohamed;Toxicol. Appl. Pharmacol.,2009

3. Arsenite down-regulates cytochrome P450 1A1 at the transcriptional and posttranslational levels in human HepG2 cells;Anwar-Mohamed;Free Radic. Biol. Med.,2010

4. Regulation of CYP1A1 by heavy metals and consequences for drug metabolism;Anwar-Mohamed;Expert Opin. Drug Metab. Toxicol.,2009

5. ATSDR, 2007. The Agency for Toxic Substances and Disease Registry, CDC. http://www.atsdr.cdc.gov/cercla/07list.html.

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