Sensitivity of butyrylcholinesterase knockout mice to (−)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmission

Author:

Duysen Ellen G.,Li Bin,Darvesh Sultan,Lockridge Oksana

Publisher

Elsevier BV

Subject

Toxicology

Reference50 articles.

1. Role of butyrylcholinesterase in canine tracheal smooth muscle function;Adler;FEBS Lett.,1990

2. Reduced acetylcholine receptor density, morphological remodeling, and butyrylcholinesterase activity can sustain muscle function in acetylcholinesterase knockout mice;Adler;Muscle Nerve,2004

3. Prophylaxis against soman inhalation toxicity in guinea pigs by pretreatment alone with human serum butyrylcholinesterase;Allon;Toxicol. Sci.,1998

4. Practical Statistics For Medical Research;Altman,1999

5. Mechanism of inhibition of cholinesterases by huperzine A;Ashani;Biochem. Biophys. Res. Commun.,1992

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