The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/−) and TP53(−/−) cells-Reference-Cited by-同舟云学术

The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/−) and TP53(−/−) cells

Published:2018-04 Issue: Volume:398-399 Page:1-12
ISSN:0300-483X
Container-title:Toxicology
language:en
Short-container-title:Toxicology

Author:

Willis Alexandra J.,Indra Radek,Wohak Laura E.,Sozeri Osman,Feser Kerstin,Mrizova Iveta,Phillips David H.,Stiborova Marie,Arlt Volker M.

Funder

Cancer Research UK

Wellcome Trust

Natural Environmental Research Council

National Institute for Health Research Health Protection Research Unit

Grant Agency of Czech Republic

MSc Programme in Biomedical and Molecular Sciences Research at King’s College London

PhD studentship from the Institute of Cancer Research

Publisher

Elsevier BV

Subject

Toxicology

Reference57 articles.

1. Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2;Aimova;Interdiscip. Toxicol.,2008

2. Mutational signatures associated with tobacco smoking in human cancer;Alexandrov;Science,2016

3. Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice;Arlt;Carcinogenesis,2008

4. Pulmonary inflammation impacts on CYP1A1-mediated respiratory tract DNA damage induced by the carcinogenic air pollutant benzo[a]pyrene;Arlt;Toxicol. Sci.,2015

5. Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolising activity of luminal muscle-invasive bladder cancers;Baker;Mol. Carcinog.,2018

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