TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation
Author:
Ho Jessica Sook Yuin, Mok Bobo Wing-Yee, Campisi Laura, Jordan TristanORCID, Yildiz SonerORCID, Parameswaran Sreeja, Wayman Joseph A., Gaudreault Natasha N., Meekins David A., Indran Sabarish V., Morozov Igor, Trujillo Jessie D., Fstkchyan Yesai S., Rathnasinghe Raveen, Zhu Zeyu, Zheng Simin, Zhao Nan, White KrisORCID, Ray-Jones Helen, Malysheva Valeriya, Thiecke Michiel J.ORCID, Lau Siu-Ying, Liu Honglian, Zhang Anna Junxia, Lee Andrew Chak-YiuORCID, Liu Wen-Chun, Jangra Sonia, Escalera Alba, Aydillo TeresaORCID, Melo Betsaida Salom, Guccione Ernesto, Sebra Robert, Shum ElaineORCID, Bakker JanORCID, Kaufman David A.ORCID, Moreira Andre L., Carossino MarianoORCID, Balasuriya Udeni B.R., Byun MinjiORCID, Albrecht Randy A., Schotsaert Michael, Garcia-Sastre Adolfo, Chanda Sumit K., Miraldi Emily R., Jeyasekharan Anand D., TenOever Benjamin R.ORCID, Spivakov MikhailORCID, Weirauch Matthew T.ORCID, Heinz SvenORCID, Chen Honglin, Benner ChristopherORCID, Richt Juergen A., Marazzi Ivan
Funder
JPB Foundation Defense Advanced Research Projects Agency Swiss National Science Foundation US Department of Homeland Security NIH Burroughs Wellcome Fund NIAID US Department of Defense
Subject
General Biochemistry, Genetics and Molecular Biology
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