Ligand-Dependent Modulation of G Protein Conformation Alters Drug Efficacy-Reference-Cited by-同舟云学术

Ligand-Dependent Modulation of G Protein Conformation Alters Drug Efficacy

Published:2016-10 Issue:3 Volume:167 Page:739-749.e11
ISSN:0092-8674
Container-title:Cell
language:en
Short-container-title:Cell

Author:

Furness Sebastian George Barton,Liang Yi-Lynn,Nowell Cameron James,Halls Michelle Louise,Wookey Peter John,Dal Maso Emma,Inoue Asuka,Christopoulos Arthur,Wootten Denise,Sexton Patrick Michael

Funder

National Health and Medical Research Council (NHMRC)

NHMRC

NHMRC Principal Research Fellow

NHMRC Senior Principal Research Fellow

NHMRC RD Wright Fellow

NHMRC Career Development Fellow

JST, PRESTO

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference48 articles.

1. Prolonged calcitonin receptor signaling by salmon, but not human calcitonin, reveals ligand bias;Andreassen;PLoS ONE,2014

2. A highly effective dominant negative alpha s construct containing mutations that affect distinct functions inhibits multiple Gs-coupled receptor signaling pathways;Berlot;J. Biol. Chem.,2002

3. GTP regulates binding of agonists to alpha 2-adrenergic receptors in human platelets;Brodde;Arch. Int. Pharmacodyn. Ther.,1982

4. Gi protein activation in intact cells involves subunit rearrangement rather than dissociation;Bünemann;Proc. Natl. Acad. Sci. USA,2003

5. A role for the calcitonin receptor to limit bone loss during lactation in female mice by inhibiting osteocytic osteolysis;Clarke;Endocrinology,2015

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