mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient-Reference-Cited by-同舟云学术

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mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient

Published:2017-10 Issue:3 Volume:171 Page:642-654.e12
ISSN:0092-8674
Container-title:Cell
language:en
Short-container-title:Cell

Author:

Wyant Gregory A.,Abu-Remaileh Monther,Wolfson Rachel L.,Chen Walter W.,Freinkman Elizaveta,Danai Laura V.,Vander Heiden Matthew G.,Sabatini David M.

Funder

NIH

Department of Defense

EMBO Long-Term Fellowship

National Defense Science & Engineering Graduate Fellowship

Lustgarten Foundation

SU2C

NCI

Howard Hughes Medical Institute

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference56 articles.

1. Cytoplasmic components in hepatic cell lysosomes;Ashford;J. Cell Biol.,1962

2. Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1;Bar-Peled;Cell,2012

3. A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1;Bar-Peled;Science,2013

4. Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins;Bar-Sagi;Science,1986

5. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine;Boussif;Proc. Natl. Acad. Sci. USA,1995

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