Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin-Reference-Cited by-同舟云学术

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin

Published:2019-02 Issue:4 Volume:176 Page:702-715.e14
ISSN:0092-8674
Container-title:Cell
language:en
Short-container-title:Cell

Author:

Xu Hui,Li Tianbo,Rohou Alexis,Arthur Christopher P.,Tzakoniati Foteini,Wong Evera,Estevez Alberto,Kugel Christine,Franke Yvonne,Chen Jun,Ciferri Claudio,Hackos David H.,Koth Christopher M.,Payandeh Jian

Funder

Medical Research Council

U.S. Department of Energy

DOE Office of Biological and Environmental Research

National Institutes of Health

National Institute of General Medical Sciences

Industrial Macromolecular Crystallography Association

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference63 articles.

1. PHENIX: a comprehensive Python-based system for macromolecular structure solution;Adams;Acta Crystallogr. D Biol. Crystallogr.,2010

2. Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist;Ahuja;Science,2015

3. Gating currents;Bezanilla;J. Gen. Physiol.,2018

4. Deconstructing voltage sensor function and pharmacology in sodium channels;Bosmans;Nature,2008

5. Alpha-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels;Campos;J. Gen. Physiol.,2008

Cited by 147 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Optimizing Nav1.7‐Targeted Analgesics: Revealing Off‐Target Effects of Spider Venom‐Derived Peptide Toxins and Engineering Strategies for Improvement;Advanced Science;2024-09-09

2. A Deep Learning Approach to Uncover Voltage-Gated Ion Channels’ Intermediate States;The Journal of Physical Chemistry B;2024-08-30

3. CaV1.1 voltage-sensing domain III exclusively controls skeletal muscle excitation-contraction coupling;Nature Communications;2024-08-28

4. Structural basis of inhibition of human Na_V1.8 by the tarantula venom peptide Protoxin-I;2024-08-28

5. Ion channels in osteoarthritis: emerging roles and potential targets;Nature Reviews Rheumatology;2024-08-09