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β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections

  • Published:2017-06 Issue:6 Volume:21 Page:707-718.e8
  • ISSN:1931-3128
  • Container-title:Cell Host & Microbe
  • language:en
  • Short-container-title:Cell Host & Microbe

Author:

Grassmé Heike,Henry Brian,Ziobro Regan,Becker Katrin Anne,Riethmüller Joachim,Gardner Aaron,Seitz Aaron P.,Steinmann Joerg,Lang Stephan,Ward Christopher,Schuchman Edward H.,Caldwell Charles C.,Kamler Markus,Edwards Michael J.,Brodlie Malcolm,Gulbins Erich

Funder

DFG

NIH

MRC Clinician Scientist Fellowship

Publisher

Elsevier BV

Subject

Virology,Microbiology,Parasitology

Reference53 articles.

1. Long-term pulmonal therapy of cystic fibrosis-patients with amitriptyline;Adams;Cell. Physiol. Biochem.,2016

2. Ion composition and rheology of airway liquid from cystic fibrosis fetal tracheal xenografts;Baconnais;Am. J. Respir. Cell Mol. Biol.,1999

3. Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis;Becker;Am. J. Respir. Cell Mol. Biol.,2010

4. Role of CD95 in pulmonary inflammation and infection in cystic fibrosis;Becker;J. Mol. Med.,2012

5. Lysosomal accumulation of cholesterol and sphingomyelin: evidence for inhibition of acid sphingomyelinase;Bhuvaneswaran;Eur. J. Cell Biol.,1985

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