Rational Engineering and Characterization of an mAb that Neutralizes Zika Virus by Targeting a Mutationally Constrained Quaternary Epitope-Reference-Cited by-同舟云学术

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Rational Engineering and Characterization of an mAb that Neutralizes Zika Virus by Targeting a Mutationally Constrained Quaternary Epitope

Published:2018-05 Issue:5 Volume:23 Page:618-627.e6
ISSN:1931-3128
Container-title:Cell Host & Microbe
language:en
Short-container-title:Cell Host & Microbe

Author:

Tharakaraman Kannan,Watanabe Satoru,Chan Kuan Rong,Huan Jia,Subramanian Vidya,Chionh Yok Hian,Raguram Aditya,Quinlan Devin,McBee Megan,Ong Eugenia Z.,Gan Esther S.,Tan Hwee Cheng,Tyagi Anu,Bhushan Shashi,Lescar Julien,Vasudevan Subhash G.,Ooi Eng Eong,Sasisekharan Ram

Funder

NIH

National Research Foundation

NMRC

Publisher

Elsevier BV

Subject

Virology,Microbiology,Parasitology

Reference40 articles.

1. Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification;Balsitis;PLoS Pathog.,2010

2. Structural basis of potent Zika-dengue virus antibody cross-neutralization;Barba-Spaeth;Nature,2016

3. Prospects for a Zika virus vaccine;Barouch;Immunity,2017

4. High resolution single particle refinement in EMAN2.1;Bell;Methods,2016

5. The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity;Beltramello;Cell Host Microbe,2010

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