First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells

Author:

Trzonkowski Piotr,Bieniaszewska Maria,Juścińska Jolanta,Dobyszuk Anita,Krzystyniak Adam,Marek Natalia,Myśliwska Jolanta,Hellmann Andrzej

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference17 articles.

1. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J. Immunol.,1995

2. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans;Roncarolo;Nat. Rev. Immunol.,2007

3. Differences in kinetics of donor lymphoid cells in response to G-CSF administration may affect the incidence and severity of acute GvHD in respective HLA-identical sibling recipients;Trzonkowski;Med. Oncol.,2004

4. Association of Foxp3 regulatory gene expression with graft-versus-host disease;Miura;Blood,2004

5. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation;Hoffmann;J. Exp. Med.,2002

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